What we have made


~ 2023

Chuapoco MR, Flytzanis N, Goeden N, Octeau JC, Roxas KM, Chan KY, Scherrer J, Winchester J, Blackburn RJ, Campos LJ, Arokiaraj CM, Miles TF, Jang MJ, Vendemiatti J, Deverman BE, Pickel J, Fox AS, Gradinaru V. (2023) “Intravenous gene transfer throughout the brain of infant Old World primates using AAV”, Nature Nanotechnology, accepted.

Jang MJ, Coughlin GM, Jackson CR, Chen X, Chuapoco MR, Vendemiatti JL, Wang ZA, Gradinaru V. (2023) “Spatial transcriptomics for profiling the tropism of viral vectors in tissues”, Nature Biotechnology. [article] [research briefing]

Kahan A, Greenbaum A, Jang MJ, Robinson JE, Cho JR, Chen X, Kassraian P, Wagenaar DA, Gradinaru V. (2021) “Light-guided sectioning for precise localization and 3D visualization of in situ optical implants”, Cell Reports, 36(13), 109744. [article]

Kumar SR, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V. (2020) “Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types”, Nature Methods, 17, pp. 541-550. [article]

Song A, Dai W, Jang MJ, Medrano L, Li Z, Zhao H, Shao M, Tan J, Li A, Ning T, Miller MM, Armstrong B, Huss JM, Zhu Y, Liu Y, Gradinaru V, Wu X, Jiang L, Scherer PE, Wang QA. (2019) “Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue”, Journal of Clinical Investigation, 130(1), pp. 247-257. [article]

Challis RC, Kumar SR, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. (2019) “Systemic AAV vectors for widespread and targeted gene delivery in rodents”, Nature Protocols, 14, pp. 379-414. [article]

Kim JH, Jang MJ, Choi J, Lee E, Song K-D, Cho J, Kim K-T, Cha H-J, Sun W. (2018) “Optimizing tissue-clearing conditions based on analysis of the critical factors affecting tissue-clearing procedures”, Scientific Reports, 8, 12815. [article]

Patriatchi T*, Cho JR*, Merten K, Howe MW, Marley A, Xiong WH, Folk RW, Broussard GJ, Liang R, Jang MJ, Zhong H, Dombeck D, Von Zastrow M, Nimmerjahn A, Gradinaru V, Williams JT, Tian L. (2018) “Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors”, Science, 360(6396), eaat4422. [article]

Kim JY*, Kim HJ*, Jang MJ, Kim JH, Lee J-H, Lee E, Park K, Kim H, Lee J, Kwag J, Kim N, Song M-R, Sun W. (2018) “BrainFilm, a novel technique for physical compression of 3D brain slices for efficient image acquisition and post-processing”, Scientific Reports, 8, 8531. [article]

Greenbaum A, Jang MJ, Challis C, Gradinaru V. (2017) “Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology?”, BMC Biology, 15, pp.87. [article]

Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu W-L, Sanchez-Guardao L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V. (2017) “Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems”, Nature Neuroscience, 20, pp. 1172-1179 (Cover picture). [article]

Jang MJ, Kim WR, Joo S, Ryu JR, Lee E, Nam Y, Sun W. (2016) “Cell-type dependent effect of surface-patterned microdot arrays on neuronal growth”, Frontiers in Neuroscience, 10, 217. [article]

Ryu JR, Jang MJ, Jo Y, Joo S, Lee DH, Lee BY, Nam Y, Sun W. (2016) “Synaptic compartmentalization by micropatterned masking of a surface adhesive cue in cultured neurons”, Biomaterials, 92, pp. 46-56. [article]

Kang K, Park Y-S, Park M, Jang MJ, Kim S-M, Lee J, Choi JY, Jung DH, Chang Y-T, Yoon M-H, Lee JS, Nam Y, Choi IS. (2016) “Axon-First Neuritogenesis on Vertical Nanowires”, Nano Letters, 16(1), pp. 675-680. [article]

Jang MJ, Nam Y. (2015) “NeuroCa: integrated framework for systematic analysis of spatiotemporal neuronal activity patterns from large-scale optical recording data”, Neurophotonics, 2(3), 035003. [article]

Jang MJ, Nam Y. (2015) “Agarose-assisted micro-contact printing for high-quality biomolecular micropatterns”, Macromolecular Bioscience, 15(5), pp. 613-621 (Cover picture). [article]

Kim WR*, Jang MJ*, Joo S, Sun W, Nam Y. (2014) “Surface-printed microdot array chips for the quantification of axonal collateral branching of a single neuron in vitro”, Lab on a Chip, 14, pp. 799-805 (*co-first authors). [article]

Moon Y, Kim JY, Kim WR, Kim HJJang MJ, Nam Y, Kim K, Sun W. (2013) “Function of ezrin-radixin-moesin proteins in migration of subventricular zone-derived neuroblasts following traumatic brain injury”, Stem Cells, 31(8), pp. 1696-1705. [article]

Jang MJ, Nam Y. (2012) “Geometric effect of cell adhesive polygonal micropatterns on neuritogenesis and axon guidance”, Journal of Neural Engineering, 9(4), 046019 (Selected as Highlights of 2012 in Journal of Neural Engineering). [article]

Jang MJ, Nam Y. (2012) “Aqueous micro-contact printing of cell-adhesive biomolecules for patterning neuronal cell cultures”, BioChip Journal, 6(2), pp. 107-113. [article]

Cho WK, Kang K, Kang G, Jang MJ, Nam Y, Choi IS. (2010) “Pitch-dependent acceleration of neurite outgrowth on nanostructured anodized aluminum oxide substrates”, Angew. Chem. Int. Ed., 122(52), pp. 10312-10316 (Cover picture). [article]

Jang MJ, Namgung S, Hong S, Nam Y. (2010) “Directional neurite growth using carbon nanotube patterned substrates as a biomimetic cue”, Nanotechnology, 21(23), 235102. [article]